The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
May. 14, 2020
Expression of sars-cov-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
Applicant:
David Gordon Bermudes, Woodland Hills, CA (US);
Inventor:
David Gordon Bermudes, Woodland Hills, CA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); C12N 1/20 (2006.01); C12N 15/70 (2006.01); A61K 39/108 (2006.01); C12R 1/19 (2006.01);
U.S. Cl.
CPC ...
A61K 39/215 (2013.01); A61K 39/0258 (2013.01); C12N 1/20 (2013.01); C12N 15/70 (2013.01); C12R 1/19 (2013.01);
Abstract
A live genetically engineered bacterium, comprising a genetically engineered construct comprising a nucleic acid sequence encoding at least one portion of a SARS-CoV-2 antigen, the live genetically engineered bacterium being adapted for administration to a human or animal and colonization of at least one tissue under non-lethal conditions. The antigen is preferably the SARS-CoV-2 spike protein. The nucleic acid sequence preferably includes an associated promoter.