The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Mar. 15, 2013
Applicant:
Bavarian Nordic A/s, Kvistgaard, DK;
Inventors:
Henning Lauterbach, Echinq, DE;
Hubertus Hochrein, Munich, DE;
Assignee:
Bavarian Nordic A/S, Kvistgaard, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/00 (2013.01); A61K 39/0005 (2013.01); A61K 39/00117 (2018.08); A61K 39/001102 (2018.08); A61K 39/001103 (2018.08); A61K 39/001106 (2018.08); A61K 39/001112 (2018.08); A61K 39/001113 (2018.08); A61K 39/001119 (2018.08); A61K 39/001124 (2018.08); A61K 39/001128 (2018.08); A61K 39/001129 (2018.08); A61K 39/001132 (2018.08); A61K 39/001134 (2018.08); A61K 39/001135 (2018.08); A61K 39/001138 (2018.08); A61K 39/001144 (2018.08); A61K 39/001152 (2018.08); A61K 39/001156 (2018.08); A61K 39/001157 (2018.08); A61K 39/001161 (2018.08); A61K 39/001162 (2018.08); A61K 39/001164 (2018.08); A61K 39/001171 (2018.08); A61K 39/001172 (2018.08); A61K 39/001176 (2018.08); A61K 39/001181 (2018.08); A61K 39/001182 (2018.08); A61K 39/001184 (2018.08); A61K 39/001186 (2018.08); A61K 39/001188 (2018.08); A61K 39/001189 (2018.08); A61K 39/001191 (2018.08); A61K 39/001192 (2018.08); A61K 39/001194 (2018.08); A61K 39/001195 (2018.08); A61K 39/001197 (2018.08); A61K 39/12 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55516 (2013.01); C12N 2710/24034 (2013.01); C12N 2710/24143 (2013.01); C12N 2760/14134 (2013.01); Y02A 50/30 (2018.01);
Abstract
Provided herein are immunogenic compositions comprising a recombinant modified vaccinia virus Ankara (MVA) comprising a nucleic acid sequence encoding a CD40 ligand (CD40L) and a nucleic acid sequence encoding a heterologous disease-associated antigen, wherein the immunogenic composition induces increases T-cell immune responses specific for the heterologous disease-associated antigen when administered to a human host, and related methods and uses.