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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10973881 B1

PDFFull Text
Date of Patent:
Apr. 13, 2021

Filed:

May. 29, 2014

Igg4 fc fragment comprising modified hinge region

Applicant:

Hanmi Pharm. Co., Ltd., Hwaseong-si, KR;

Inventors:

Sung Youb Jung, Suwon-si, KR;

Yong Ho Huh, Seoul, KR;

Sung Hee Park, Seongnam-si, KR;

Jong Soo Lee, Seongnam-si, KR;

In Young Choi, Yongin-si, KR;

Assignee:

HANMI PHARM. CO., LTD., Hwaseong-si, KR;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Phuong Huynh

Int. Cl.
CPC ...
C07K 19/00 (2006.01); A61K 47/68 (2017.01); A61K 38/19 (2006.01); C07K 14/47 (2006.01); A61K 47/60 (2017.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/193 (2013.01); A61K 47/60 (2017.08); A61K 47/68 (2017.08); A61K 47/6813 (2017.08); A61K 47/6849 (2017.08); C07K 14/47 (2013.01); C07K 16/2803 (2013.01); C07K 2317/40 (2013.01); C07K 2317/52 (2013.01); C07K 2317/53 (2013.01); C07K 2317/94 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to a modified IgG4 Fc fragment useful as a drug carrier. When the modified IgG4 Fc fragment of the present invention is combined with an arbitrary drug, the resulting drug conjugate can minimize the effector functions of the IgG4 Fc and the chain exchange with in vivo IgG while maintaining in vivo activity and improving in vivo duration of the drug conjugate.

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Jung, Sung. (2021). Igg4 fc fragment comprising modified hinge region (U.S. Patent No. 10973881). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10973881

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