The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Dec. 30, 2016
Applicant:

Marshall University Research Corporation, Huntington, WV (US);

Inventors:

Zijian Xie, Huntington, WV (US);

Joseph I. Shapiro, Huntington, WV (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/16 (2006.01); A61K 38/46 (2006.01); C07K 14/00 (2006.01); A61P 9/10 (2006.01); A61K 38/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/005 (2013.01); A61K 9/0048 (2013.01); A61K 38/10 (2013.01); A61K 38/162 (2013.01); A61K 38/46 (2013.01); A61P 9/10 (2018.01); C12Y 306/03009 (2013.01);
Abstract

Methods for treating retinopathy are provided and include administering an effective amount of a polypeptide antagovist of a Na/K ATPase/Src receptor complex to a subject. The retinopathy can include diabetic retinopathy. Methods of decreasing angiogenesis in a retinal vasculature are also provided and include the step of administering, such as by intravitreous injection, a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof.


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