The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Jun. 23, 2017
Applicant:

Cornell University, Ithaca, NY (US);

Inventors:

Justin Wilson, Ithaca, NY (US);

Kevin Knopf, Kensington, CT (US);

Sierra Marker, Ithaca, NY (US);

Assignee:

CORNELL UNIVERSITY, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/24 (2019.01); A61K 31/555 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 33/24 (2013.01); A61K 31/555 (2013.01); A61P 35/00 (2018.01);
Abstract

A composition comprising the following structure: (formula I) wherein Re represents a rhenium ion having a +1 charge; (formula II) represents an uncharged bidentate bicyclic ligand bonded to the rhenium (Re) by two ring nitrogen (N) atoms; and L is a neutral ligand independently selected from CO and neutral phosphine molecules, wherein at least one of the L groups is a CO molecule; and Xrepresents a non-coordinating monovalent anion; wherein (formula II) is unsubstituted or substituted on any of its two rings, and said neutral phosphine molecule may or may not contain a phosphorus atom as a ring phosphorus atom; provided that, if (formula II) is unsubstituted, then one or two of said L groups are selected from said neutral phosphine molecules, with the provision that at least one of the neutral phosphine molecules has a phosphorus atom as a ring phosphorus atom. Methods for treating cancer by administering the above complex are also disclosed.


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