The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 13, 2021

Filed:

Oct. 25, 2016
Applicants:

Alex Cortez, San Diego, CA (US);

Bernhard Hubert Geierstanger, Solana Beach, CA (US);

Timothy Z. Hoffman, San Diego, CA (US);

Shailaja Kasibhatla, San Diego, CA (US);

Tetsuo Uno, San Diego, CA (US);

Xing Wang, San Diego, CA (US);

Tom Yao-hsiang Wu, San Diego, CA (US);

Inventors:

Alex Cortez, San Diego, CA (US);

Bernhard Hubert Geierstanger, Solana Beach, CA (US);

Timothy Z. Hoffman, San Diego, CA (US);

Shailaja Kasibhatla, San Diego, CA (US);

Tetsuo Uno, San Diego, CA (US);

Xing Wang, San Diego, CA (US);

Tom Yao-Hsiang Wu, San Diego, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); A61K 47/68 (2017.01); C07D 487/04 (2006.01); C07H 15/26 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 31/52 (2013.01); A61K 47/6849 (2017.08); C07D 487/04 (2013.01); C07H 15/26 (2013.01); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/94 (2013.01);
Abstract

Provided herein are antibody conjugates comprising toll-like receptor agonists and the use of such conjugates for the treatment of cancer. In some embodiments, the conjugates comprise anti-HER2 antibodies.


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