The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2021
Filed:
Apr. 24, 2020
Fulcrum Therapeutics, Inc., Cambridge, MA (US);
Ivan Viktorovich Efremov, Chestnut Hill, MA (US);
Steven Kazmirski, Sherborn, MA (US);
Qingyi Li, Somerville, MA (US);
Lorin A. Thompson, III, Cohasset, MA (US);
Owen Brendan Wallace, Brookline, MA (US);
Shawn Donald Johnstone, Saint-Lazare, CA;
Feng Zhou, Dollards-des-Ormeaux, CA;
Peter Rahl, Natick, MA (US);
Fulcrum Therapeutics, Inc., Cambridge, MA (US);
Abstract
The invention relates to modulators of Embryonic Ectoderm Development (EED) and/or Polycomb Repressive Complex 2 (PRC2) useful in the treatment of disorders and diseases associated with EEC and PRC2, being macrocyclic azolopyridine derivatives and compositions thereof of Formula I: or a pharmaceutically acceptable salt, prodrug, solvate, hydrate, enantiomer, isomer, or tautomer thereof, wherein X, X, X, A, A, Y, R, R, R, and Rare as described herein.