The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Feb. 14, 2019
Applicants:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

University of Oklahoma Health Sciences Center, Oklahoma City, OK (US);

Inventors:

Adam R. Hall, Clemmons, NC (US);

Elaheh Rahbar, Winston-Salem, NC (US);

Paul DeAngelis, Edmond, OK (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44791 (2013.01); G01N 33/48721 (2013.01);
Abstract

In one aspect, methods of biomolecular analysis are described herein. Briefly, a method comprises providing a composition comprising glycosaminoglycans and contacting the composition with a membrane comprising at least one nanopore. An electric field is applied across the nanopore, and data of glycosaminoglycan translocation events through the nanopore are recorded. A molecular weight distribution of the glycosaminoglycans is derived from the data.


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