The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Dec. 14, 2017
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Andreas Schade, Essen, DE;
Mike Küster, Düsseldorf, DE;
Klaus Ochmann, Leverkusen, DE;
Michael Harnau, Leichlingen, DE;
Karl-Hermann Koeching, Dormagen, DE;
Nils Burkhardt, Velbert, DE;
Bernd Kalthof, Wuppertal, DE;
Linn Schneider, Düsseldorf, DE;
Georg Schmidt, Wuppertal, DE;
BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;
Abstract
A method and a system for rapid kinetic fluorescence measurement in high-throughput screening with high time-resolution includes providing a microtiter plate having a transparent base and multiple assay wells, a dispensing system arranged above the microtiter plate for simultaneously adding liquid into multiple assay wells, an illumination system beneath the microtiter plate for illuminating the multiple assay wells simultaneously through the transparent base, a detection system for detecting electromagnetic radiation from the multiple assay wells simultaneously through the transparent base, adding 0.3-300 μl of liquid per assay well from the dispensing system into the multiple assay wells, illuminating the multiple assay wells simultaneously through the transparent base using the illumination system before or from the time point of the start of the addition, detecting the electromagnetic radiation from the multiple assay wells simultaneously at a time interval of 1-1000 ms between individual measurement points.