The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Jul. 24, 2020
Applicant:

New England Biolabs, Inc., Ipswich, MA (US);

Inventors:

Nathan Tanner, West Newbury, MA (US);

Yinhua Zhang, North Reading, MA (US);

Gregory Patton, Peabody, MA (US);

Guoping Ren, Danvers, MA (US);

Zhiru Li, Lexington, MA (US);

Nicole Nichols, Reading, MA (US);

Assignee:

New England Biolabs, Inc., Ipswich, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/78 (2006.01); C12Q 1/6844 (2018.01); C12Q 1/70 (2006.01); G16B 25/20 (2019.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/701 (2013.01); G01N 21/78 (2013.01);
Abstract

Kits and methods are provided for performing multiplex LAMP reactions. These kits and methods are directed to specific and sensitive methods of target nucleic acid detection and more specifically pathogen diagnostics such as detection of Coronavirus. The kits and methods utilize a plurality of sets of oligonucleotide primers for targeting different template sequences in a single nucleic acid target. The kits and methods also include guanidium salts that enhance the sensitivity of the assay.


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