The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Oct. 17, 2019
Nanomedical Diagnostics, Inc., San Diego, CA (US);
Pieter van Rooyen, La Jolla, CA (US);
Mitchell Lerner, La Jolla, CA (US);
Paul Hoffman, La Jolla, CA (US);
Brett R. Goldsmith, San Diego, CA (US);
Cardea Bio, Inc., San Diego, CA (US);
Abstract
Chemically-sensitive field effect transistors for biosensor chips and system are disclosed. The itransisitors have a multi-layered structure for performing a set of measurements of a biological reaction involving a binding event for one or more biological analytes that may be label-free. The multilayer structure includes a first insulating layer above a substrate layer and a source electrode and a drain electrode disposed positioned over the first insulating layer; a second insulating layer above the first insulating layer and proximate the source and drain electrodes forming side wall members of a well for a fluid comprising the analytes; a 2D graphene layer forming a channel between source and drain electrodes; a solution gate, formed by fluid flowed over the channel, configured to enable determining differences between one or more sample I-Vg curves having a shifted and changed shape relative to a reference curve; embodiments may include ion-selective membranes and/or ion getters.