The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Mar. 16, 2018
Applicants:
Trustees of Boston University, Boston, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Timothy Kuan-Ta Lu, Cambridge, MA (US);
Robert James Citorik, Kingston, NH (US);
James Collins, Newton, MA (US);
Russell-John Krom, Boston, MA (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
Trustees of Boston University, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C12N 15/74 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); C12N 7/00 (2013.01); C12N 15/70 (2013.01); C12N 2795/14132 (2013.01); C12N 2795/14143 (2013.01); C12N 2795/14171 (2013.01); C12N 2830/55 (2013.01);
Abstract
Various aspects and embodiments of the present disclosure are directed to methods and compositions for functionalizing endogenous bacteria in vivo. The methods include delivering to endogenous bacterial cells a recombinant bacteriophage or phagemid that is engineered to contain at least one genetic circuit.