The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Nov. 16, 2017
Applicant:
Technion Research & Development Foundation Limited, Haifa, IL;
Inventors:
Michal Amit, Misgav, IL;
Joseph Itskovitz-Eldor, Haifa, IL;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0735 (2010.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0606 (2013.01); C12N 5/0031 (2013.01); C12N 5/0037 (2013.01); C12N 5/0043 (2013.01); C12N 2501/115 (2013.01); C12N 2501/15 (2013.01); C12N 2501/235 (2013.01); C12N 2501/2306 (2013.01); C12N 2533/12 (2013.01); C12N 2533/90 (2013.01);
Abstract
A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention.