The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Feb. 26, 2018
Applicant:

General Electric Company, Schenectady, NY (US);

Inventors:

Antonio Caiafa, Albany, NY (US);

Vasile Bogdan Neculaes, Niskayuna, NY (US);

Assignee:

GENERAL ELECTRIC COMPANY, Schenectady, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/42 (2006.01); C12M 1/00 (2006.01); C12M 1/36 (2006.01); C12M 3/00 (2006.01); C12N 13/00 (2006.01); A61B 5/15 (2006.01); G01N 35/02 (2006.01); G01N 33/487 (2006.01); A61K 35/00 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
C12M 35/02 (2013.01); A61B 5/150343 (2013.01); A61B 5/150755 (2013.01); C12M 23/42 (2013.01); C12M 29/12 (2013.01); C12M 41/48 (2013.01); C12N 13/00 (2013.01); G01N 33/48707 (2013.01); G01N 35/025 (2013.01); G01N 35/026 (2013.01); A61K 35/00 (2013.01); G01N 33/49 (2013.01);
Abstract

Disclosed herein are multi-cuvette cartridges, flow cells, and electrical pulse systems for treatment of large volumes of biological samples with pulsed electric fields. The multi-cuvette cartridges systems may include mechanical motors for automatic positioning and alignment between the cuvettes and the electrodes of the electrical pulse systems. The flow cell systems may include fluidic systems, such as pumps, nozzles and valves, which may operate in coordination with the electrical systems for efficient exposition of biological samples. Embodiments having flow cell systems that allow 'on-demand' production of activated sample are also disclosed.


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