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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10968277 B1

PDFFull Text
Expired
Date of Patent:
Apr. 06, 2021

Filed:

Oct. 21, 2016

Gene signatures for determining icos expression

Applicant:

Jounce Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Jason Windham Reeves, Boston, MA (US);

Igor Feldman, Jamaica Planin, MA (US);

Christopher Harvey, Boston, MA (US);

Sriram Sathyanarayanan, Lexington, MA (US);

Heather Hirsch, Brookline, MA (US);

Lauren Pepper MacKenzie, Cambridge, MA (US);

Amit Deshpande, Cambridge, MA (US);

Stephen Sazinsky, Melrose, MA (US);

Jennifer S. Michaelson, Brighton, MA (US);

Kutlu Goksu Elpek, Arlington, MA (US);

Assignee:

Jounce Therapeutics, Inc., Cambridge, MA (US);

Attorney:

McNeill Baur PLLC

Primary Examiner:

James Martinell

Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C12Q 1/6886 (2018.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61P 35/00 (2018.01); C12Q 1/6886 (2013.01); A61K 39/0011 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/20 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/73 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Gene expression signatures correlating to ICOS expression levels are provided. Methods of treatment comprising determining ICOS expression levels using gene signatures in patients and administering anti-ICOS antibodies are also provided.

Find Patent Forward Citations

Reeves, Jason. (2021). Gene signatures for determining icos expression (U.S. Patent No. 10968277). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10968277

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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