The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Mar. 15, 2017
Applicant:
Acceleron Pharma Inc., Cambridge, MA (US);
Inventors:
Jasbir Seehra, Lexington, MA (US);
Jennifer Lachey, Arlington, MA (US);
Assignee:
ACCELERON PHARMA INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01); C07K 14/47 (2006.01); A61K 38/17 (2006.01); A61P 21/00 (2006.01); C07K 16/26 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4707 (2013.01); A61K 38/1709 (2013.01); A61P 21/00 (2018.01); C07K 14/4708 (2013.01); C07K 16/26 (2013.01); C07K 16/2869 (2013.01); C07K 2317/76 (2013.01);
Abstract
In certain aspects, the present invention provides compositions and methods for inducing utrophin expression in muscle with an ActRIIB protein as therapy for muscular dystrophy. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand.