The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Mar. 29, 2018
Applicants:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Scohia Pharma, Inc, Kanagawa, JP;

Inventors:

Seiji Miwatashi, Tokyo, JP;

Yasufumi Miyamoto, Kanagawa, JP;

Koji Watanabe, Kanagawa, JP;

Yayoi Nakayama, Kanagawa, JP;

Yuko Hitomi, Kanagawa, JP;

Jumpei Aida, Kanagawa, JP;

Nobuyuki Takakura, Kanagawa, JP;

Hideki Furukawa, Kanagawa, JP;

Naoyoshi Noguchi, Kanagawa, JP;

Yasuhiro Hirata, Kanagawa, JP;

Shizuo Kasai, Kanagawa, JP;

Toshitake Kobayashi, Kanagawa, JP;

Tsuyoshi Maekawa, Kanagawa, JP;

Satoshi Sasaki, Kanagawa, JP;

Shigemitsu Matsumoto, Kanagawa, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); C07D 211/22 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 491/052 (2013.01); C07D 211/22 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01);
Abstract

Provided is a novel aromatic ring compound which may have a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof may have a GPR40 agonist activity and a GLP-1 secretagogue action, may be useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and may afford superior efficacy.


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