The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Sep. 06, 2017
Applicants:

Shanghai Haihe Pharmaceutical Co., Ltd., Shanghai, CN;

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Inventors:

Xuxing Chen, Shanghai, CN;

Meiyu Geng, Shanghai, CN;

Lei Jiang, Shanghai, CN;

Yi Chen, Shanghai, CN;

Jianhua Cao, Shanghai, CN;

Qingyun Jiang, Shanghai, CN;

Qianqian Shen, Shanghai, CN;

Jian Ding, Shanghai, CN;

Yucai Yao, Shanghai, CN;

Zhao Zhao, Shanghai, CN;

Yuanfang Xiong, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/444 (2006.01); A61P 35/00 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61P 37/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61P 35/00 (2018.01); A61P 37/06 (2018.01); C07D 519/00 (2013.01);
Abstract

The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.


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