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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10968203 B1

PDFFull Text
Date of Patent:
Apr. 06, 2021

Filed:

May. 24, 2018

Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating ire1-related diseases and disorders

Applicants:

Genentech, Inc., South San Francisco, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Marie-Gabrielle Braun, South San Francisco, CA (US);

Paul Gibbons, San Francisco, CA (US);

Wendy Lee, San Ramon, CA (US);

Cuong Ly, Burlingame, CA (US);

Joachim Rudolph, Burlingame, CA (US);

Jacob Schwarz, San Ramon, CA (US);

Avi Ashkenazi, San Mateo, CA (US);

Leo Fu, Shanghai, CN;

Tommy Lai, Shanghai, CN;

Fei Wang, Shanghai, CN;

Ramsay Beveridge, Quebec, CA;

Liang Zhao, Montreal, CA;

Assignees:

Genentech, Inc., South San Francisco, CA (US);

The Regents of the University of California, Oakland, CA (US);

Attorney:

Alston & Bird LLP

Primary Examiner:

Brenda L Coleman

Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 45/06 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/506 (2013.01); A61P 35/00 (2018.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); A61K 45/06 (2013.01);
Abstract

Described herein are pyrimidinyl-pyridyloxy-naphthyl compounds with inositol requiring enzyme 1 (IRE1) modulation activity or function having the Formula I or I' structure:

Find Patent Forward Citations

Braun, Marie-Gabrielle. (2021). Pyrimidinyl-pyridyloxy-naphthyl compounds and methods of treating ire1-related diseases and disorders (U.S. Patent No. 10968203). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10968203

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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