The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Oct. 11, 2019
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Peter Wipf, Pittsburgh, PA (US);

Chaemin Lim, Pittsburgh, PA (US);

Wei Qian, Pittsburgh, PA (US);

Bennett Van Houten, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); C07D 311/92 (2006.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 311/92 (2013.01); A61K 45/06 (2013.01); A61P 25/28 (2018.01); A61P 35/00 (2018.01); C07D 405/12 (2013.01);
Abstract

Compounds are provided that are useful in treating cancer and neurodegeneration. The compounds comprise a β-lapachone or β-lapachone derivative tricyclic ortho-naphthoguinone moiety linked to a mitochondria-targeting moiety, for example as defined with respect to Formula (I): or a pharmaceutically-acceptable salt thereof. Pharmaceutical compositions are provided comprising the composition. Methods of treatment of cancer and neurodegenerative disorders also are provided.


Find Patent Forward Citations

Wipf, Peter. (2021). Substituted β-lapachones for treating cancer (U.S. Patent No. 10968196). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10968196

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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