The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

Dec. 02, 2015
Applicant:

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Michiel Luc Maria Van Gool, Madrid, ES;

José Ignacio Andrés-Gil, Madrid, ES;

Manuel Jesús Alcázar-Vaca, Toledo, ES;

Guy Maurits R. Bormans, Rotselaar, BE;

Sofie Jeanne Leopoldine Celen, Tessenderlo, BE;

Joost Verbeek, Enkhuizen, NL;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/04 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); C07B 59/00 (2006.01); C07D 419/14 (2006.01); C07D 487/04 (2006.01); A61B 6/03 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0459 (2013.01); A61P 25/18 (2018.01); A61P 25/24 (2018.01); C07B 59/002 (2013.01); C07D 419/14 (2013.01); C07D 487/04 (2013.01); A61B 6/037 (2013.01); A61K 2123/00 (2013.01); C07B 2200/05 (2013.01); C07K 14/70571 (2013.01);
Abstract

The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.


Find Patent Forward Citations

Loading…