The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Aug. 14, 2015
Applicants:
Pfizer Inc., New York, NY (US);
Rinat Neuroscience Corp., South San Franciso, CA (US);
Inventors:
Russell George Dushin, Old Lyme, CT (US);
Pavel Strop, San Mateo, CA (US);
Magdalena Grazyna Dorywalska, Redwood City, CA (US);
Ludivine Moine, Uncasville, CT (US);
Assignees:
PFIZER INC., New York, NY (US);
RINAT NEUROSCIENCE CORP., New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/65 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/65 (2017.08); A61K 47/64 (2017.08); A61K 47/6803 (2017.08); A61K 2039/505 (2013.01); C07K 2317/94 (2013.01); C07K 2319/01 (2013.01); C07K 2319/35 (2013.01);
Abstract
The present invention provides stability-modulated antibody-drug conjugates, stability-modulating linker components used to make these stability-modulated antibody-drug conjugates, therapeutic methods using stability-modulated antibody-drug conjugates, and methods of making stability modulating linkers and stability-modulated antibody-drug conjugates.