The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2021
Filed:
Jan. 26, 2016
Lubris Llc, Framingham, MA (US);
Gregory D. Jay, Norfolk, MA (US);
Benjamin D. Sullivan, San Diego, CA (US);
Tannin Avery Schmidt, Calgary, CA;
Khaled Elsaid, Boston, MA (US);
Edward R. Truitt, San Diego, CA (US);
Roman Krawetz, Calgary, CA;
Jawed Fareed, Westchester, IL (US);
Lubris LLC, Framingham, MA (US);
Abstract
Disclosed herein are methods of using PRG4 glycoprotein, also known as lubricin, to reduce, inhibit, or down-regulate pro-inflammatory pathways in patients at risk of or suffering from an inflammatory response or allergy symptom through CD44 antagonization, regulating pro-inflammatory cytokine production, inhibiting NF-κB translocation and/or facilitating removal of inflammation-inducing cellular or matrix debris or allergens.