The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 2021

Filed:

May. 03, 2016
Applicant:

Cytometix, Inc., Bayside, WI (US);

Inventors:

Lane Brostrom, Bayside, WI (US);

Henry Bordas-Murphy, Wauwatosa, WI (US);

John R. Falck, Dallas, TX (US);

Assignee:

Cytometix, Inc., Milwaukee, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 9/48 (2006.01); A61K 31/202 (2006.01); A61P 29/00 (2006.01); A61K 31/05 (2006.01); A61K 31/164 (2006.01); A61K 31/4468 (2006.01); A61K 31/381 (2006.01); A61K 31/135 (2006.01); A61K 31/16 (2006.01); A61K 31/197 (2006.01);
U.S. Cl.
CPC ...
A61K 31/05 (2013.01); A61K 9/4825 (2013.01); A61K 9/4858 (2013.01); A61K 9/4891 (2013.01); A61K 31/135 (2013.01); A61K 31/16 (2013.01); A61K 31/164 (2013.01); A61K 31/197 (2013.01); A61K 31/202 (2013.01); A61K 31/381 (2013.01); A61K 31/4468 (2013.01); A61K 45/06 (2013.01); A61P 29/00 (2018.01);
Abstract

The present invention provides a system enabling the oral delivery of therapeutics derived from polyunsaturated fatty acids (PUFAs), their metabolites and derivatives, including, eicosanoids, prostaglandins, prostacyclins, leukotrienes, resolvins, endocannabinoids, thromboxanes, epoxyeicosa-trienoic acids (EETs), hydroxyeicostetraenoic acids (HETEs), and CMX-020. The delivery system includes a vehicle comprising a purified docosahexaenoic acid (DHA) in triglyceride or ester form; a purified eicosapentaenoic acid (EPA) in triglyceride or ester form; a combination of DHA, EPA in either triglyceride or ester forms; or a modified DHA, EPA, or omega-3 fatty acid analog; and optionally, an antioxidant, a surfactant, a solubilizer, a stabilizer, a lubricant, or a pH/tonicity adjustment agent.


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