The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Nov. 30, 2015
Biomerieux, Marcy l'Etoile, FR;
Hospices Civils DE Lyon, Lyons, FR;
BIOMERIEUX, Marcy l'Etoile, FR;
HOSPICES CIVILS DE LYON, Lyons, FR;
Abstract
A method for estimating the affinity ϕ of a first DNA strand, or 'probe', to be hybridized with a second DNA strand, or 'target', to form a hybrid of length L, the method comprising: in each division of a set of M divisions of the hybrid, counting the number of times in which each hybrid of a set of P DNA strand hybrids is present in the division, the hybrids being of length k less than the length L, or “k-hybrids”; for each combination of mismatches of a set of L combinations of mismatches in a hybrid of length Lbp, determining whether the pair of mismatches is present in the hybrid; and calculating the affinity ϕ according to the relation: