The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2021

Filed:

Jan. 18, 2017
Applicants:

Robert Alfano, New York, NY (US);

Lingyan Shi, New York, NY (US);

Inventors:

Robert Alfano, New York, NY (US);

Lingyan Shi, New York, NY (US);

Assignee:

Robert Alfano, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G02B 21/00 (2006.01); G06N 10/00 (2019.01); A61B 18/20 (2006.01); A61N 5/06 (2006.01); G01N 33/483 (2006.01); G02F 1/35 (2006.01); G02F 1/355 (2006.01); G02F 1/365 (2006.01); A61B 5/00 (2006.01); A61B 17/00 (2006.01); A61B 18/18 (2006.01); A61N 5/067 (2006.01);
U.S. Cl.
CPC ...
G02B 21/0064 (2013.01); A61B 18/20 (2013.01); A61N 5/0622 (2013.01); G01N 33/4833 (2013.01); G02B 21/0032 (2013.01); G02B 21/0084 (2013.01); G02F 1/3515 (2013.01); G02F 1/3536 (2013.01); G02F 1/3551 (2013.01); G02F 1/365 (2013.01); G06N 10/00 (2019.01); A61B 5/0066 (2013.01); A61B 2017/00508 (2013.01); A61B 2018/1807 (2013.01); A61B 2018/2065 (2013.01); A61N 2005/067 (2013.01); A61N 2005/0659 (2013.01); G02F 1/355 (2013.01); G02F 2001/3528 (2013.01);
Abstract

Supercontinuum (SC) (˜400 nm to ˜2500 nm) and a microscope produce enhanced microscopic images on sub-micron to cm scale of linear (χ) and nonlinear (χ, χ, χ. . . ) processes via resonance including linear absorption, SHG, THG, SRG, SRL, SRS, 2PEF, 3PEF, 4PEF, and inverse Raman in a microscope for 2D and 3D imaging. Images and processes in 2D and 3D arise from electronic and vibrational resonances transitions in biological and medical tissues, cells, condensed matter applications. Resonant Stimulated Raman Scattering (RSRS) is proposed to improve vibrational imaging of biomaterials by using part of SC. Quantum mechanical processes from SC for 2 and 4 photons to improve resolution and imaging using entangled photons are described. The addition of time measuring instrument like a Streak camera and the scattering coefficient μ' can be mapped to create images of tissue and biomaterial in 5D: Space (3D), Time, and Wavelength.


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