The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2021

Filed:

Oct. 07, 2016
Applicant:

Washington University, St. Louis, MO (US);

Inventors:

Sheng-Kwei Song, Manchester, MO (US);

Qing Wang, St. Louis, MO (US);

Yong Wang, St. Louis, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/44 (2006.01); A61B 5/055 (2006.01); G01R 33/563 (2006.01);
U.S. Cl.
CPC ...
G01R 33/56341 (2013.01); A61B 5/055 (2013.01);
Abstract

A method of performing diffusion basis spectrum imaging (DBSI) within a tissue of a patient using diffusion magnetic resonance data acquired from a portion of the tissue is disclosed. The diffusion magnetic resonance data includes a plurality of diffusion MR signals associated with one voxel and the one voxel represents an image of the portion of the tissue. The method includes computing an isotropic diffusion portion of the diffusion magnetic resonance data representing isotropic diffusion within the one voxel and dividing the isotropic diffusion portion, which includes a fraction of the diffusion magnetic resonance data representing isotropic diffusion, into a restricted isotropic diffusion portion and a non-restricted isotopic diffusion portion. The restricted isotropic diffusion portion includes a fraction of the isotropic diffusion portion with an apparent diffusion coefficient of less than 0.3 and the non-restricted isotopic diffusion portion includes a fraction of the isotropic diffusion portion with an apparent diffusion coefficient of at least 0.3.


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