The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Aug. 13, 2018
Bgi Tech Solutions Co., Ltd, Guangdong, CN;
Beijing Institute for Cancer Research, Beijing, CN;
Rui Xing, Beijing, CN;
Youyong Lu, Beijing, CN;
Zhibo Gao, Beijing, CN;
Wenmei Li, Beijing, CN;
Jiantao Cui, Beijing, CN;
Lin Li, Beijing, CN;
Longyun Chen, Beijing, CN;
BGI TECH SOLUTIONS CO., LTD, Guangdong, CN;
BEIJING INSTITUTE FOR CANCER RESEARCH, Beijing, CN;
Abstract
The present invention relates to methods, kits, and compositions for detecting and/or diagnosing metastatic potential of cancer cells or for evaluating prognosis in a patient with cancer by detection of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule. The present invention also relates to the use of the protein expression level of an HLA class I molecule and/or the copy number variation of a polynucleotide encoding the HLA class I molecule as a prognosis biomarker and metastasis predictive biomarker of cancer.