The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2021

Filed:

Feb. 26, 2020
Applicants:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Inventors:

Aruna Ayer, Santa Clara, CA (US);

Cleoma Renetta Arnold, San Jose, CA (US);

Arkadiusz Bibillo, Cupertino, CA (US);

Mara Boenitz-Dulat, Tutzing, DE;

Barbara Eckert, El Cerrito, CA (US);

Ilya Lederman, San Francisco, CA (US);

Colin Alexander McGaw, Santa Clara, CA (US);

Charles Wayan Schwab, San Ramon, CA (US);

Tyler O'Brien Shultz, Santa Clara, CA (US);

Shawn Suko, El Sobrante, CA (US);

Eileen Thai, San Jose, CA (US);

Bigna Woersdoerfer, Basel, CH;

David Daniel Wunderlich, Penzberg, DE;

Assignees:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1252 (2013.01); C07K 2319/21 (2013.01); C12Y 207/07007 (2013.01);
Abstract

Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365Q, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, I644, T647, I648, T651, I652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.


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