The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Jan. 06, 2017
Applicant:
Cynity Co., Ltd., Tokyo, JP;
Inventors:
Takahiro Ochiya, Tokyo, JP;
Takeshi Katsuda, Tokyo, JP;
Assignee:
Cynity Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/407 (2015.01); C12Q 1/02 (2006.01); A61P 1/16 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0672 (2013.01); A61K 35/407 (2013.01); A61P 1/16 (2018.01); C12Q 1/02 (2013.01); G01N 33/5014 (2013.01); G01N 33/5067 (2013.01); C12N 2501/15 (2013.01); C12N 2501/727 (2013.01);
Abstract
The present invention provides a method for producing hepatic stem/progenitor cells from mammal hepatocytes, comprising bringing a TGFβ-receptor inhibitor, and optionally a GSK3 inhibitor and/or a ROCK inhibitor into contact with the hepatocytes in vitro.