The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Jun. 07, 2019
Applicant:
Neurimmune Holding Ag, Schlieren, CH;
Inventors:
Fabio Montrasio, Schindellegi, CH;
Jan Grimm, Dübendorf, CH;
Assignee:
Neurimmune Holding AG, Schlieren, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); A61P 25/28 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61P 25/28 (2018.01); G01N 33/6896 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2800/2814 (2013.01);
Abstract
Provided are novel human-derived dipeptide repeat (DPR) specific antibodies as well as synthetic variants and biotechnological derivatives thereof, preferably capable of binding C9ORF72 DPRs, as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for DPRs and DPR proteins such C9ORF72 DPRs are also disclosed. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.