The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Aug. 29, 2019
Applicant:
Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);
Inventors:
Ryan Hudson, San Jose, CA (US);
Daniel D. Long, San Francisco, CA (US);
Donna A. A. Wilton, San Francisco, CA (US);
Mandy Loo, San Jose, CA (US);
Patrick J. Brassil, Redwood City, CA (US);
Assignee:
Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/26 (2006.01); A61P 1/00 (2006.01); C07D 487/04 (2006.01); C07H 1/00 (2006.01); C12P 17/16 (2006.01);
U.S. Cl.
CPC ...
C07H 15/26 (2013.01); A61P 1/00 (2018.01); C07D 487/04 (2013.01); C07H 1/00 (2013.01); C12P 17/165 (2013.01);
Abstract
The invention provides compounds which are prodrugs of a JAK inhibitor agent for the targeted delivery of the JAK inhibitor to the gastrointestinal tract of a mammal. The invention also provides pharmaceutical compositions comprising the compounds, methods of using the compounds to treat gastrointestinal inflammatory diseases, and processes and intermediates useful for preparing the compounds.