The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Feb. 06, 2020
Legochem Biosciences, Inc., Daejeon, KR;
Dae Yon Lee, Daejeon, KR;
Sang Eun Chae, Daejeon, KR;
Eun Mi Jung, Daejeon, KR;
Eun Hye Yang, Daejeon, KR;
Yoon Jeong Choi, Daejeon, KR;
Chul-Woong Chung, Daejeon, KR;
Ju Hyun Shin, Daejeon, KR;
Yun Ki Kim, Daejeon, KR;
Hyun Jin Kwon, Daejeon, KR;
Jeong Hee Ryu, Daejeon, KR;
Eun Hye Ban, Daejeon, KR;
Yong Zu Kim, Daejeon, KR;
Yeong Soo Oh, Daejeon, KR;
Jeiwook Chae, Daejeon, KR;
LegoChem Biosciences, Inc., Daejeon, KR;
Abstract
The present invention relates to novel compounds as autotoxin inhibitors for treatment and prophylaxis of conditions or a disorder caused by autotaxin activation or increased concentration of lysophosphatidic acid, and also a pharmaceutical composition containing the same. The novel compounds of the present invention are autotoxin inhibitors, and by inhibiting the production of lysophosphatidic acid, they are useful for treatment or prophylaxis of cardiovascular disorder, cancer, metabolic disorder, kidney disorder, liver disorder, inflammatory disorder, nervous system disorder, respiratory system disorder, fibrotic disease, ocular disorder, cholestatic and other forms of chronic pruritus, or acute or chronic organ transplant rejection.