The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Feb. 15, 2019
Applicant:
The Usa, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Martin John Schnermann, Rockville, MD (US);
Michael Philip Luciano, Frederick, MD (US);
Roger Rauhauser Nani, Frederick, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07D 209/10 (2006.01); G01N 33/533 (2006.01); G01N 33/58 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C07D 209/10 (2013.01); A61K 49/0032 (2013.01); A61K 49/0058 (2013.01); G01N 21/6428 (2013.01); G01N 33/533 (2013.01); G01N 33/582 (2013.01); G01N 2021/6439 (2013.01);
Abstract
Heptamethine cyanine fluorophore conjugates and conjugate precursors are disclosed. Methods of using the conjugates and conjugate precursors are also disclosed. The disclosed conjugates are neutral zwitterionic molecules and exhibit little or no aggregation.