The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2021

Filed:

Jan. 22, 2020
Applicant:

Jeju National University Industry-academic Cooperation Foundation, Jeju-do, KR;

Inventors:

You-Jin Jeon, Jeju-do, KR;

BoMi Ryu, Jeju-do, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/09 (2006.01); A61K 36/03 (2006.01); A23L 33/10 (2016.01); A61P 21/00 (2006.01); C07C 43/295 (2006.01);
U.S. Cl.
CPC ...
C07C 43/295 (2013.01); A23L 33/10 (2016.08); A61K 36/03 (2013.01); A23V 2002/00 (2013.01);
Abstract

Disclosed herein are hexadecaphlorethol (HdP), which is a novel compound isolated from, and the use thereof in anti-diabetic treatment and exercise performance improvement. The novel compound HdP has the activity of inhibiting α-glucosidase, inducing glucose uptake into differentiated myoblast C2C12 cells, reducing blood glucose levels in zebrafish which have reduced insulin secretion through treatment with alloxan, increasing an intracellular level of calcium ions necessary for muscle contraction and exercise performance in zebrafish, and inducing uptake of glucose, an energy source necessary for muscle contraction, into cells.


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