The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Sep. 29, 2016
Applicants:
Rhythm Pharmaceuticals, Inc., Boston, MA (US);
Charité —universitätsmedizin Berlin, Berlin, DE;
Inventors:
Leonardus H. T. Van Der Ploeg, Newton, MA (US);
Bart Henderson, Belmont, MA (US);
Peter Kuhnen, Berlin, DE;
Assignees:
RHYTHM PHARMACEUTICALS, INC., Boston, MA (US);
CHARITÉ—UNIVERSITÄTSMEDIZIN BERLIN, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/12 (2006.01); C07K 14/72 (2006.01); C07K 7/06 (2006.01); A61P 3/04 (2006.01); A61P 3/10 (2006.01); A61K 9/00 (2006.01); C07K 7/54 (2006.01); C07K 14/685 (2006.01);
U.S. Cl.
CPC ...
A61K 38/12 (2013.01); A61K 9/0019 (2013.01); A61P 3/04 (2018.01); A61P 3/10 (2018.01); C07K 7/06 (2013.01); C07K 7/54 (2013.01); C07K 14/685 (2013.01); C07K 14/723 (2013.01);
Abstract
The disclosure is related to a method of treating a disorder, such as Prader Willi Syndrome (PWS), obesity or hyperphagia, in a subject using a melanocortin-4 receptor (MC4R) agonist. Also described is method of treating a subject having a deficiency in the pro-opiomelanocortin (POMC)-MC4R pathway, such as a POMC-null or a PCSK-null subject, using a MC4R agonist.