The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2021

Filed:

Jul. 01, 2019
Applicant:

New York University, New York, NY (US);

Inventors:

Thomas Wisniewski, Staten Island, NY (US);

Daryl Spinner, Staten Island, NY (US);

Henrieta Scholtzova, Fords, NJ (US);

Richard Kascsak, Morganville, NJ (US);

Assignee:

New York University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7088 (2006.01); A61K 39/00 (2006.01); A61P 25/28 (2006.01); A61K 48/00 (2006.01); C12N 15/85 (2006.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 48/00 (2013.01); A61P 25/28 (2018.01); C12N 15/85 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/57 (2013.01); C12N 15/117 (2013.01);
Abstract

The present invention is directed to a method of preventing or reducing amyloid deposition in a subject. This method involves selecting a subject with amyloid deposits and stimulating the innate immune system of the selected subject under conditions effective to reduce the amyloid deposits. Also disclosed is a method of preventing or treating cerebral amyloidosis and Alzheimer's Disease in a subject by administering to the selected subject an agent that stimulates the innate immune system. In addition, a composition useful for the stimulation of the innate immune system of a subject exhibiting symptoms associated with amyloid deposition is disclosed.


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