The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Sep. 18, 2019
Applicant:
Taiho Pharmaceutical Co., Ltd., Chiyoda-ku, JP;
Inventor:
Kenichiro Yoshida, Tsukuba, JP;
Assignee:
TAIHO PHARMACEUTICAL CO., LTD., Chiyoda-ku, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/513 (2006.01); A61K 31/506 (2006.01); A61K 31/7072 (2006.01); A61P 13/12 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/513 (2013.01); A61K 31/506 (2013.01); A61K 31/7072 (2013.01); A61P 13/12 (2018.01); A61P 35/00 (2018.01);
Abstract
A method for treating cancer in patients with creatinine clearance of 15 mL/min or more and less than 30 mL/min, including dividing a combination drug containing α,α,α-trifluorothymidine (FTD) and 5-chloro-6-[(2-iminopyrrolidine-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride in a molar ratio of 1:0.5, in a dose of 30 to 50 mg/m/day as FTD-equivalent, into two to four times a day, and orally administering it to the patient.