The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Mar. 14, 2014
Applicant:
Alumend, Llc, Sioux Falls, SD (US);
Inventors:
Barbara R. Haberer, Hartford, SD (US);
Therese J. Downey, Brookings, SD (US);
Ronald E. Utecht, Madison, SD (US);
Assignee:
Alumend, LLC, Sioux Falls, SD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/473 (2006.01); A61K 9/00 (2006.01); A61K 41/00 (2020.01); A61N 5/06 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/473 (2013.01); A61K 9/0019 (2013.01); A61K 41/0042 (2013.01); A61K 45/06 (2013.01); A61N 5/062 (2013.01); A61N 2005/0602 (2013.01);
Abstract
Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque, as well as acutely restoring the vascular compliance at the treatment site of the blood vessel, while maintaining luminal gain during angioplasty. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also disclosed.