The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Nov. 28, 2018
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Raghu Kalluri, Houston, TX (US);
Sónia Melo, Maia, PT;
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/11 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 9/127 (2006.01); A23L 29/20 (2016.01); A23L 29/238 (2016.01); A23L 29/25 (2016.01); A23L 33/185 (2016.01); A23L 29/231 (2016.01); A23L 29/256 (2016.01); A23L 29/262 (2016.01); A23L 29/212 (2016.01); A23L 29/269 (2016.01); A23L 33/00 (2016.01); A23L 23/10 (2016.01); A23L 25/10 (2016.01); A23L 27/60 (2016.01); A23L 9/10 (2016.01); A23C 19/09 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01); C12N 15/88 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A23C 19/0904 (2013.01); A23L 9/10 (2016.08); A23L 23/10 (2016.08); A23L 25/10 (2016.08); A23L 27/60 (2016.08); A23L 29/20 (2016.08); A23L 29/212 (2016.08); A23L 29/231 (2016.08); A23L 29/238 (2016.08); A23L 29/25 (2016.08); A23L 29/256 (2016.08); A23L 29/262 (2016.08); A23L 29/269 (2016.08); A23L 33/185 (2016.08); A23L 33/40 (2016.08); A61K 9/0019 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12N 15/88 (2013.01); A23V 2002/00 (2013.01); A61K 9/127 (2013.01); A61K 9/5068 (2013.01); C12N 2310/14 (2013.01);
Abstract
The present invention provides lipid-based nanoparticles (e.g., liposomes or exosomes) having CD47 on their surface and comprising a therapeutic agent (e.g., a therapeutic protein, an antibody, an inhibitory RNA, and/or a small molecule drug). Furthermore, the present invention provides for use of such lipid-based nanoparticles in therapy.