The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2021
Filed:
Dec. 17, 2015
Applicant:
Ares Trading S.a., Aubonne, CH;
Inventors:
Angelika Freitag, Martinsried, DE;
Andrea Hawe, Martinsried, DE;
Gianluca Rinaldi, Monterotondo, IT;
Alessandra Del Rio, Rome, IT;
Assignee:
ARES TRADING S.A., Aubonne, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 19/00 (2006.01); A61K 38/17 (2006.01); A61K 47/18 (2017.01); A61K 9/00 (2006.01); A61K 47/26 (2006.01); A61K 9/08 (2006.01); A61K 47/06 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 38/1793 (2013.01); A61K 47/06 (2013.01); A61K 47/18 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); C07K 14/70578 (2013.01); C07K 14/7151 (2013.01); C07K 19/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to novel liquid protein formulations, particularly arginine-free liquid pharmaceutical compositions of etanercept. The invention employs particular combinations and classes of buffer systems, tonicifiers, and sugar stabilisers, optionally alongside polar ionisable amino acids (e.g. aspartic acid, glutamic acid, histidine, and lysine), to afford a viable and storable drug product.