The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2021
Filed:
Sep. 30, 2016
Applicant:
Api Corporation, Tokyo, JP;
Inventors:
Ryoma Miyake, Tokyo, JP;
Hiroshi Kawabata, Tokyo, JP;
Assignee:
API CORPORATION, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 17/12 (2006.01); C12N 9/10 (2006.01); C12N 9/06 (2006.01); C12N 9/02 (2006.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C12P 17/12 (2013.01); C12N 9/0016 (2013.01); C12N 9/0022 (2013.01); C12N 9/0071 (2013.01); C12N 9/1096 (2013.01); C12Y 114/11028 (2013.01); C12N 15/09 (2013.01);
Abstract
A novel method of producing high-purity hydroxy-L-pipecolic acids in an efficient and inexpensive manner while suppressing the production of hydroxy-L-proline is provided. The method includes allowing an L-pipecolic acid hydroxylase, a microorganism or cell having the ability to produce the enzyme, a processed product of the microorganism or cell, and/or a culture liquid comprising the enzyme and obtained by culturing the microorganism or cell, to act on L-pipecolic acid as a substrate in the presence of 2-oxoglutaric acid and ferrous ion, wherein the L-pipecolic acid hydroxylase has the properties: