The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2021
Filed:
Mar. 15, 2019
Applicant:
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Inventors:
Satwik Kamtekar, Mountain View, CA (US);
Jeremiah Hanes, Woodside, CA (US);
Assignee:
Pacific Biosciences of California, Inc., Menio Park, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12Q 1/6869 (2018.01); C12M 1/42 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1276 (2013.01); C12M 1/42 (2013.01); C12N 9/1241 (2013.01); C12P 19/34 (2013.01); C12Q 1/6869 (2013.01);
Abstract
Provided are compositions comprising recombinant polymerases that include amino acid substitutions, insertions, deletions, and/or exogenous features that confer modified properties upon the polymerase for sequencing RNA or RNA/DNA templates. Polymerases that topologically encircle the template nucleic acid are provided. Also provided are methods of using such polymerases to make a DNA or to sequence a template comprising RNA.