The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2021
Filed:
Mar. 07, 2018
Applicant:
Biogen MA Inc., Cambridge, MA (US);
Inventors:
David J. Burke, Oakland, CA (US);
Shaun E. Buckley, San Francisco, CA (US);
Sherwood Russ Lehrman, Los Altos, CA (US);
Barbara Horsey O'Connor, San Carlos, CA (US);
James Callaway, San Diego, CA (US);
Christopher P. Phillips, Doyleston, PA (US);
Assignee:
BIOGEN MA INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 47/02 (2006.01); A61K 47/26 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2839 (2013.01); A61K 39/39591 (2013.01); A61K 47/02 (2013.01); A61K 47/26 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01);
Abstract
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.