The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2021

Filed:

Apr. 14, 2017
Applicant:

Ra Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Kristopher Josephson, San Carlos, CA (US);

Zhong Ma, Lexington, MA (US);

Yili Sun, Cambridge, MA (US);

Nathan Ezekiel Nims, Winchester, MA (US);

Kathleen Seyb, Wakefield, MA (US);

Sylvia Tobe, Cambridge, MA (US);

Ping Ye, Lexington, MA (US);

Douangsone D. Vadysirisack, Boston, MA (US);

Guo-Qing Tang, Acton, MA (US);

Douglas A. Treco, Arlington, MA (US);

Assignee:

RA PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 14/82 (2006.01); C07K 7/08 (2006.01); G01N 33/574 (2006.01); A61K 47/65 (2017.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01); A61K 47/14 (2017.01); C07K 7/54 (2006.01);
U.S. Cl.
CPC ...
C07K 14/82 (2013.01); A61K 38/00 (2013.01); A61K 47/14 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61P 35/00 (2018.01); C07K 7/08 (2013.01); C07K 7/54 (2013.01); G01N 33/574 (2013.01);
Abstract

The present invention provides Ras modulators including inhibitors and/or antagonists of Ras, Ras binding, and Ras-dependent cell signaling activity. Also provided are methods of utilizing the Ras modulators as therapeutics.


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