The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2021

Filed:

Jun. 08, 2018
Applicant:

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Richard M Van Rijn, West Lafayette, IN (US);

Mark S Cushman, West Lafayette, IN (US);

Markus Lill, West Lafayette, IN (US);

Robert J Cassell, West Lafayette, IN (US);

Amr Hamed Mahmoud Abdallah, West Lafayette, IN (US);

Mohamed S. A. Elsayed, West Lafayette, IN (US);

Assignee:

Purdue Research Foundation, West Lafayette, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/12 (2006.01); A61P 25/32 (2006.01); C07D 405/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); A61P 25/32 (2018.01); C07D 405/12 (2013.01); C07D 417/12 (2013.01);
Abstract

The present disclosure relates to novel δ-opioid receptor agonists, and the method of making and using the novel δ-opioid receptor agonists. The novel δ-opioid receptor agonists are selective δ-opioid receptor agonists that have substantially no beta-arrestin 2 recruitment or low beta-arrestin 2 recruitment. The novel δ-opioid receptor agonists may be used for the treatment for alcohol use disorders and other co-occurring psychiatric disorders.


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