The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2021

Filed:

Sep. 23, 2020
Applicant:

Battelle Memorial Institute, Columbus, OH (US);

Inventors:

Patrick Ganzer, Columbus, OH (US);

Seyed Masoud Loeian, Columubs, OH (US);

David A Friedenberg, Worthington, OH (US);

Doug Weber, Pittsburgh, PA (US);

Assignee:

BATTELLE MEMORIAL INSTITUTE, Columbus, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/36 (2006.01);
U.S. Cl.
CPC ...
A61N 1/36114 (2013.01); A61N 1/36139 (2013.01);
Abstract

Closed-loop stimulation of the Vagus nerve in response to a detected myocardial ischemia state within a therapeutic window can mitigate or reverse effects of the ischemia. This window is between 0 and 50 seconds of the onset of ischemia, before the myocardial ischemia reaches a statistically significant evolution level. A properly trained machine learning system such as a long short-term memory system can be used to analyze cardiovascular features and detect myocardial ischemia within the therapeutic window.


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