The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2021

Filed:

Apr. 17, 2017
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Ebru Oral, Newton, MA (US);

Jeremy Suhardi, Boston, MA (US);

Orhun Muratoglu, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/54 (2006.01); A61K 35/32 (2015.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01);
U.S. Cl.
CPC ...
A61L 27/54 (2013.01); A61K 35/32 (2013.01); A61L 27/3608 (2013.01); A61L 27/3683 (2013.01); A61L 27/3687 (2013.01); A61L 27/3691 (2013.01); A61L 27/3821 (2013.01); A61L 2300/428 (2013.01); A61L 2430/02 (2013.01);
Abstract

Systems and methods of protecting allograft against radiation damage are disclosed. Systems and methods of incorporating additives such as radioprotectants into allograft tissue are also disclosed. The systems and methods comprise providing an allograft; cleaning the allograft; contacting the allograft with at least one radioprotectant, thereby obtaining a radioprotectant-doped allograft; contacting the radioprotectant-doped allograft with a supercritical fluid, thereby obtaining a radioprotectant doped and homogenized allograft.


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