The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2021

Filed:

May. 09, 2017
Applicants:

Lawrence Livermore National Security, Llc, Livermore, CA (US);

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Inventors:

Aida E. Rieder, Westbrook, CT (US);

Teresa B. De Los Santos, Miller Place, NY (US);

Luis L. Rodriguez, Clinton, CT (US);

Devendra Rai, Old Saybrook, CT (US);

Fayna C. Diaz-San Segundo, Ronkonkoma, NY (US);

Paul D. Hoeprich, Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/135 (2006.01); C12N 7/00 (2006.01); G01N 33/53 (2006.01); C12Q 1/70 (2006.01); A61K 39/12 (2006.01); A61P 31/14 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/135 (2013.01); A61K 39/12 (2013.01); A61P 31/14 (2018.01); C12N 7/00 (2013.01); C12Q 1/70 (2013.01); G01N 33/53 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/55572 (2013.01); C12N 2770/32122 (2013.01); C12N 2770/32134 (2013.01); C12N 2770/32141 (2013.01); C12N 2770/32162 (2013.01);
Abstract

Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.


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