The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2021
Filed:
Apr. 29, 2019
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Benjamin Levi, Ann Arbor, MI (US);
Shailesh Agarwal, Ypsilanti, MI (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 19/08 (2006.01); A61K 31/198 (2006.01); A61K 31/436 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 31/198 (2013.01); A61K 31/436 (2013.01); A61P 19/08 (2018.01);
Abstract
The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1α (Hif-1α) inhibitor to the subject. In various embodiments, the Hif-1α inhibitor is PX-478, rapamycin, or digoxin.